What causes sadness and depression?

[Agua del Cielo]

I am not a big fan of psychotropic drugs (i hope this translation is correct) such as anti-depressants and stuff.
I think it can numb you to the point where its hard to further evolve, not speaking of other side effects.

hOWEVER, there are mental and emotional conditions, that make it almost impossible to live ones life. In such a case, such medication can be a great relief, enabling a mental and emotional state that makes it possible to live and work through all that stuff.
In such a case it would be highly irresponsible to just stop that medication.

It would be like "oh,there s too much stuff for you too handle? Great, just stop medication and lets see what happens, if you get even more of that stuff!"

Also, as much as medicines like for example ayahuasca can aid healing and spiritual growth if the conditions are RIGHT, i would clearly not advise this under no circumstamces to a person that is struck by a condition like schizophrenia or in an acute psychosis and has not (yet) the background necessary to deal with the material that is possibly being surfaced by those means.

Given a very stable "personality", a lot of experience with working through difficult emotional stuff and an experienced "sitter" as well as the opportunity to be accompanied in the following timespan by an loving and understanding entity, medicine plants can definitely aid in uncovering otherwise unaccessable material.
If these factors are not given, which definitely wouldnt be so in the case discussed, one would run into a very high risk of inviting much much more imbalances that could in any way be handled, thus worsening the situation heavily.